ZOCOR (simvastatin) Tablets
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چکیده
----------------------------INDICATIONS AND USAGE --------------------------- ZOCOR is an HMG-CoA reductase inhibitor (statin) indicated as an adjunctive therapy to diet to: • Reduce the risk of total mortality by reducing CHD deaths and reduce the risk of non-fatal myocardial infarction, stroke, and the need for revascularization procedures in patients at high risk of coronary events. (1.1) • Reduce elevated total-C, LDL-C, Apo B, TG and increase HDL-C in patients with primary hyperlipidemia (heterozygous familial and nonfamilial) and mixed dyslipidemia. (1.2) • Reduce elevated TG in patients with hypertriglyceridemia and reduce TG and VLDL-C in patients with primary dysbeta lipoproteinemia. (1.2) • Reduce total-C and LDL-C in adult patients with homozygous familial hypercholesterolemia. (1.2) • Reduce elevated total-C, LDL-C, and Apo B in boys and postmenarchal girls, 10 to 17 years of age with heterozygous familial hypercholesterolemia after failing an adequate trial of diet therapy. (1.2, 1.3)
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ZOCOR (simvastatin) Tablets
----------------------------INDICATIONS AND USAGE ---------------------------ZOCOR is an HMG-CoA reductase inhibitor (statin) indicated as an adjunctive therapy to diet to: • Reduce the risk of total mortality by reducing CHD deaths and reduce the risk of non-fatal myocardial infarction, stroke, and the need for revascularization procedures in patients at high risk of coronary events. (1.1) • R...
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BACKGROUND It is commonly agreed that people with a high blood LDL-cholesterol will have a higher risk of coronary artery disease (CAD) than people with low blood LDL-cholesterol. Due to the increasingly high costs of medication in Thailand, the government has set up several measures to combat the problem. One of such strategies is to promote the utilization of locally manufactured drug product...
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Daily doses of 10 mg of policosanol have been shown to be equally effective in lowering total or LDL cholesterol as the same dose of simvastatin (Zocor) or pravastatin (Pravachol). At dosages of up to 20 mg per day, policosanol is safe and well tolerated, as studies of >3 years of therapy indicate.” The authors concluded that policosanol seems to be a very promising phytochemical alternative to...
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